James B Kirkland Selected Research

Niacin (Nicotinic Acid)

10/2018	Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements for NAD+ Synthesis.
1/2018	Niacin.
5/2012	Niacin requirements for genomic stability.
1/2012	Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis.
5/2010	Poly ADP-ribose polymerase-1 and health.
12/2009	Niacin status impacts chromatin structure.
4/2009	Niacin status and treatment-related leukemogenesis.
1/2009	Niacin status, NAD distribution and ADP-ribose metabolism.
11/2008	Niacin deficiency causes oxidative stress in rat bone marrow cells but not through decreased NADPH or glutathione status.
6/2008	The role of dietary niacin intake and the adenosine-5'-diphosphate-ribosyl cyclase enzyme CD38 in spatial learning ability: is cyclic adenosine diphosphate ribose the link between diet and behaviour?

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James B Kirkland Research Topics

Disease

11	Neoplasms (Cancer) 01/2018 - 01/2002
8	Genomic Instability 05/2012 - 01/2003
6	Leukemia 01/2012 - 01/2002
5	Carcinogenesis 05/2010 - 01/2002
3	Chromosome Breakage 05/2012 - 04/2009
3	Leukopenia 01/2003 - 01/2002
2	Skin Neoplasms (Skin Cancer) 05/2012 - 01/2003
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2018
1	Metabolic Diseases (Metabolic Disease) 01/2018
1	Acute Disease 05/2010
1	Stroke (Strokes) 05/2010
1	Myocardial Infarction 05/2010
1	Septic Shock (Toxic Shock Syndrome) 05/2010
1	Inflammation (Inflammations) 01/2009
1	Cognitive Dysfunction 06/2008
1	Chromosomal Instability (Chromosome Stability) 12/2007
1	Chromosome Aberrations (Chromosome Abnormalities) 12/2007
1	Carcinoid Tumor (Carcinoid) 10/2005
1	Pellagra 10/2005
1	Anemia 01/2003

Drug/Important Bio-Agent (IBA)

17	Niacin (Nicotinic Acid)FDA LinkGeneric 10/2018 - 01/2002
6	Poly Adenosine Diphosphate RiboseIBA 01/2012 - 01/2002
4	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 01/2008 - 01/2002
2	NAD (NADH)IBA 01/2018 - 10/2005
2	DNA (Deoxyribonucleic Acid)IBA 05/2012 - 12/2007
2	Antineoplastic Agents (Antineoplastics)IBA 01/2002 - 01/2002
1	VitaminsIBA 01/2018
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 05/2012
1	EnzymesIBA 05/2012
1	ChromatinIBA 12/2009
1	Pharmaceutical PreparationsIBA 01/2009
1	Cyclic ADP-Ribose (cADPR)IBA 06/2008
1	NADP (NADPH)IBA 10/2005
1	Indicators and Reagents (Reagents)IBA 10/2005
1	Serotonin (5 Hydroxytryptamine)IBA 10/2005
1	Tryptophan (L-Tryptophan)FDA Link 10/2005
1	5-Hydroxytryptophan (5 Hydroxytryptophan)IBA 10/2005
1	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2003
1	PolymersIBA 01/2003
1	Poly (ADP-Ribose) Polymerase-1IBA 01/2003

Therapy/Procedure

5	Drug Therapy (Chemotherapy) 04/2009 - 01/2002
1	Chemoprevention 01/2007
1	Nutritional Support (Artificial Feeding) 10/2005